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Located in the Presidio's Letterman District within the Thoreau Center for Sustainability, Cafe Rx is off the beaten path. You're more likely to find park workers than visitors at this reliable, reasonably priced, and unfussy walk-up eatery.
Open for breakfast and lunch, Monday through Friday from 7 am to 2:30 pm, Café Rx offers a mix of expected fare and unique gourmet bistro offerings on its eclectic menu. Chef and owner Rogelio Colindres, who opened Café Rx in 2013, is originally from El Salvador, so along with bagels, sandwiches, and salads, you'll find Latin American-inspired specials, like pupusas and tamales, on the changing daily menu.
As for its name, Rx pays homage to its building, which was originally a pharmacy in the former Letterman Hospital. Keeping with the health-inspired theme, the cafe prepares all of its food with fresh, organic, free-range, locally grown, and seasonal ingredients. It also offers options for vegetarians and those on gluten-free diets.
While you're here, don't forget to visit the China Brotsky Art Gallery just down the hall, and the life-sized bronze Yoda statue at the Letterman Digital Arts Center next door. As with the Yoda sculpture, Café Rx is a hidden, unexpected, and completely worthwhile Presidio destination.